Effect of Tween 80 on alkaloid-producing cultures of Claviceps paspali.
IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore
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http://ir.cftri.com/4051/
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| Title |
Effect of Tween 80 on alkaloid-producing cultures of Claviceps paspali.
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| Creator |
Rehacek, Z.
Basappa, S. C. |
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| Subject |
01 Alkaloid Biochemistry
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| Description |
Addition of Tween 80 to submerged cultures of Clat~e~ paajm~ (Stevens and Hall) growing
in a simple defined medium increased biomass formation and caused a temporary change in alkaloid
synthesis intensity. The Twcen-supplemented culture reached maximal alkaloid yields four days earlier
than the control. The shift of alkaloid production was associated with a shift of organic acids and amino
acids in the cell-pool. Thus the maximal formation of alkaloids was characterized by a decrease in the
amount of' citric acid, by the disappearance of succinic, fumaric and oxaloacetic acids and by increased
accumulation of methionine, cysteine, alinine and histidine. The slow alkaloid synthesis was accompanied
by a relatively high content of citric and succinic acids in the cell-pool and by the absence of methionine.
The data are consistent with the hypothesis that ergot alkaloids participate in the regulation of the metabolism
of cultures.
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| Date |
1971
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| Type |
Article
PeerReviewed |
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| Format |
pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/4051/1/Folia%20Microbiologica%2C%20Volume-16%28%20%281971%29%20110-113.pdf
Rehacek, Z. and Basappa, S. C. (1971) Effect of Tween 80 on alkaloid-producing cultures of Claviceps paspali. Folia Microbiologica, 16. pp. 110-113. |
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