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Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction.

IR@CFTRI: CSIR-Central Food Technological Research Institute, Mysore


Field	Value

Relation	http://ir.cftri.com/13163/ http://dx.doi.org/10.1016/j.fshw.2017.04.001

Title	Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction.

Creator	Mukthamba, P. Srinivasan, K.

Subject	01 Dietary Fiber 30 Spices/Condiments

Description	Soluble fiber-rich fenugreek seeds (Trigonella foenum-graecum) and garlic (Allium sativum) are understood to exert cholesterol-lowering andantioxidant effects. The cardioprotective influence of a combination of fenugreek seeds and garlic by their antioxidant influence was evaluatedin hypercholesterolemic rats administered isoproterenol. Wistar rats were maintained on high-cholesterol diet for 8 weeks along with dietaryinterventions of fenugreek (10%), garlic (2%) and their combination. Myocardial infarction was induced with isoproterenol injection. Increasedcirculatory troponin, disturbed activities of cardiac ATPases, increased serum iron and decreased ceruloplasmin confirmed myocardial infarction.Elevated lipid peroxides accompanied with reduced antioxidant molecules caused by isoproterenol and altered activities of antioxidant enzymes inserum and heart in induced myocardial necrosis were countered by dietary fenugreek, garlic, and fenugreek + garlic. Dietary fenugreek seeds andgarlic ameliorated

Date	2017

Type	Article PeerReviewed

Format	pdf

Language	en

Identifier	http://ir.cftri.com/13163/1/Food%20Science%20and%20Human%20Wellness%206%20%282017%29%2077%E2%80%9387.pdf Mukthamba, P. and Srinivasan, K. (2017) Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction. Food Science and Human Wellness, 6. pp. 77-87.