Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
|
|
| Creator |
Khan, I. A.
Mirza, Z. M. Kumar, A. Verma, V. Qazi, G. N. |
|
| Subject |
Pharmacological Sciences
|
|
| Description |
Piperine, a trans-trans isomer of 1-piperoyl-piperidine, in combination with ciprofloxacin markedly reduced
the MICs and mutation prevention concentration of ciprofloxacin for Staphylococcus aureus, including methicillin-resistant S. aureus. The enhanced accumulation and decreased efflux of ethidium bromide in the wild-type
and mutant (CIPr-1) strains in the presence of piperine suggest its involvement in the inhibition of bacterial
efflux pumps.
|
|
| Date |
2006
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://iiim.csircentral.net/379/1/10.1128AAC.50.2.810%E2%80%93812.2006.pdf
Khan, I. A. and Mirza, Z. M. and Kumar, A. and Verma, V. and Qazi, G. N. (2006) Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 50 (2). pp. 810-812. ISSN 0066-4804 |
|
| Relation |
http://dx.doi.org/10.1128/AAC.50.2.810-812.2006
http://iiim.csircentral.net/379/ |
|