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Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol:A Novel Triglyceride from Berries of Hippophae rhamnoides.

IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur

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Title Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol:A Novel Triglyceride from Berries of Hippophae rhamnoides.
 
Creator Swaroop, A
Sinha, Arun K
Chawla, R
Arora, R
Sharma, R K
Kumar, J K
 
Subject Chemical Engineering
 
Description 1,3-Dicapryloyl-2-linoleoylglycerol (1), a novel triglyceride, was isolated from berries of Hippophae rhamnoides. The structure was elucidated on the basis of MS, 1D and 2D NMR experiments including HMQC and HMBC. The metal chelating, free radical scavenging, and lipid peroxidation inhibiting properties of the compound were also estimated with particular reference to radiation protection. In case of metal chelation and superoxide ion scavenging, 1 showed maximum inhibition at 50m g/ml (11%) and 100m g/ml (55%), respectively, whereas in lipid peroxidation, 1 showed maximum inhibition (57%) at 2 mg/ml as compared to quercetin as a control.
 
Publisher The Pharmaceutical Society of Japan
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/180/1/Chem_Pharm_Bull.pdf
Swaroop, A and Sinha, Arun K and Chawla, R and Arora, R and Sharma, R K and Kumar, J K (2005) Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol:A Novel Triglyceride from Berries of Hippophae rhamnoides. Chemical and Pharmaceutical Bulletin, 53 (8). pp. 1021-1024. ISSN 0009-2363
 
Relation http://ihbt.csircentral.net/180/