An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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Creator |
Sharma, Anindra
Pandey, Jyoti Tripathi, R P |
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Date |
2009-08-31T11:34:39Z
2009-08-31T11:34:39Z 2009 |
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Identifier |
Tetrahedron Letters (2009) 50, 1812-1816
http://hdl.handle.net/123456789/490 |
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Description |
Knoevenagel/ Michael/ Aldol reactions of aromatic aldehydes and β-keto esters/ketones in a sequential manner yielded the intermediate cyclohexanones in good yields. The latter on oxidative aromatization with iodine afforded the functionalized biphenyls with at least one phenolic hydroxyl in moderate to good yields
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Format |
152965 bytes
application/pdf |
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Language |
en
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Relation |
CDRI Communication No 7552
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Subject |
Polysubstituted benzenes
Aldol reactions Michael additions Knoevenagel reaction Regioselective Hydroxylated biphenyls |
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Title |
An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones
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Type |
Article
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