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An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Sharma, Anindra
Pandey, Jyoti
Tripathi, R P
 
Date 2009-08-31T11:34:39Z
2009-08-31T11:34:39Z
2009
 
Identifier Tetrahedron Letters (2009) 50, 1812-1816
http://hdl.handle.net/123456789/490
 
Description Knoevenagel/ Michael/ Aldol reactions of aromatic aldehydes and β-keto esters/ketones in a sequential manner yielded the intermediate cyclohexanones in good yields. The latter on oxidative aromatization with iodine afforded the functionalized biphenyls with at least one phenolic hydroxyl in moderate to good yields
 
Format 152965 bytes
application/pdf
 
Language en
 
Relation CDRI Communication No 7552
 
Subject Polysubstituted benzenes
Aldol reactions
Michael additions
Knoevenagel reaction
Regioselective
Hydroxylated biphenyls
 
Title An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones
 
Type Article