Highly convenient regioselective synthesis of functionalized arylated benzene from ketene-S,S-acetal under mild conditions at room temperature
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Kumar, Vijay
Singh, Fateh V Parihar, Amrita Goel, Atul |
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| Date |
2009-08-31T06:32:36Z
2009-08-31T06:32:36Z 2009 |
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| Identifier |
Tetrahedron Lett. (2009) 50, 680-683
http://hdl.handle.net/123456789/482 |
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| Description |
A general, highly efficient synthesis of arylated benzenes from simple stitching of alpha-oxo-ketene-S,S-acetals and functionalized deoxybenzoins via a ‘lactone intermediate’ is described. This procedure offers easy access to highly functionalized arylated benzenes containing sterically demanding groups in good to excellent yields. The advantage of the procedure lies in the fabrication of arylated benzenes with desired conformational flexibility along the molecular axis at room temperature and in a transition metal-free environment through easily accessible precursors.
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| Format |
132182 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No 7254
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| Subject |
Ketene-S
S-acetal 2H-Pyran-2-one Arylated benzene Molecular propeller Quinquephenyl |
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| Title |
Highly convenient regioselective synthesis of functionalized arylated benzene from ketene-S,S-acetal under mild conditions at room temperature
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| Type |
Article
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