Stabilization of β-hairpin structures via inter-strand π-π and hydrogen bond interactions in α-, β-, γ-hybrid peptides
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Chakraborty, Tushar Kanti
Rao, K Srinivasa Kiran, M Udaya Jagadeesh, B |
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| Date |
2009-05-20T15:00:11Z
2009-05-20T15:00:11Z 2009 |
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| Identifier |
Tetrahedron Letters, 50,4350-4353
http://hdl.handle.net/123456789/443 |
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| Description |
Synthesis and conformational studies of α-, β-, γ-hybrid peptides containing a pyrrole amino acid (Paa, 1) and a furan amino acid (Faa, 2), namely Boc-β-Phe-Faa-D-Pro-Gly-Paa-β-HGly-Faa-OMe (3) and Boc-Paa-β-Phe-Faa-D-Pro-Gly-Paa-β-HGly-Faa-OMe (4), were carried out and they adopt -hairpin structures stabilized via inter-strand π-π and hydrogen bonding interactions.
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| Format |
215138 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No.7774
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| Subject |
pyrrole amino acid
furan amino acid peptidomimetics β-hairpin |
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| Title |
Stabilization of β-hairpin structures via inter-strand π-π and hydrogen bond interactions in α-, β-, γ-hybrid peptides
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| Type |
Article
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