Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles and their antimicrobial evaluation
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Saxena, Nisha
Singh, Nimisha Mishra, Mridul Keshava, G B Shiva Shukla, P K Tripathi, R P |
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| Date |
2009-02-10T19:22:38Z
2009-02-10T19:22:38Z 2008 |
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| Identifier |
JEIMC 23,476-482 (2008)
http://hdl.handle.net/123456789/334 |
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| Description |
A series of azatricyclodiones and octahydro-benzo[f]isoindoles have been synthesized by (4+2) Diels-Alder cycloaddition of maleimides with furfuryl amine. Reaction of azatricyclodiones with isocyanates led to respective ureides. All of the compounds were screened against a number of bacteria and fungi. One of the compounds (2) displayed moderate Antitubercular activity while two compounds (2) and (4) inhibited the fungal growth at 25 µg/mL.
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| Format |
130913 bytes
application/pdf |
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| Language |
en
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| Subject |
Cycloaddition
dienophile furfuryl amine azatricyclodiones octahydro-benzo[f]isoindoles |
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| Title |
Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles and their antimicrobial evaluation
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| Type |
Article
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