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Tetrabutylammonium Hydrogensulphate Catalyzed Efficient Synthesis of Glycosyl(aryl) Dihydropyrimidinones

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Dwivedi, Namrata
Mishra, Ram C
Tripathi, R P
 
Date 2009-02-10T19:22:02Z
2009-02-10T19:22:02Z
2005
 
Identifier Lett. Org. Chem. 2, 450 (2005)
http://hdl.handle.net/123456789/324
 
Description An efficient synthesis of glycosyl dihydropyrimidinones using a three-component reaction of a β-keto ester, glycosyl aldehyde, urea (or thiourea) in the presence of tetrabutylammonium hydrogensulphate and diethylene glycol as eco-friendly solvent has been reported. The reaction has been extended to the synthesis of aryl and heteroaryl dihydropyrimidinones also. The glycosyl dihydropyrimidinones were obtained in excellent yields in less time than the methods already reported.
 
Format 176656 bytes
application/pdf
 
Language en
 
Subject Aldehydes
Phase transfer catalyst
Dihydropyrimidinone
 
Title Tetrabutylammonium Hydrogensulphate Catalyzed Efficient Synthesis of Glycosyl(aryl) Dihydropyrimidinones
 
Type Article