Tetrabutylammonium Hydrogensulphate Catalyzed Efficient Synthesis of Glycosyl(aryl) Dihydropyrimidinones
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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Creator |
Dwivedi, Namrata
Mishra, Ram C Tripathi, R P |
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Date |
2009-02-10T19:22:02Z
2009-02-10T19:22:02Z 2005 |
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Identifier |
Lett. Org. Chem. 2, 450 (2005)
http://hdl.handle.net/123456789/324 |
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Description |
An efficient synthesis of glycosyl dihydropyrimidinones using a three-component reaction of a β-keto ester, glycosyl aldehyde, urea (or thiourea) in the presence of tetrabutylammonium hydrogensulphate and diethylene glycol as eco-friendly solvent has been reported. The reaction has been extended to the synthesis of aryl and heteroaryl dihydropyrimidinones also. The glycosyl dihydropyrimidinones were obtained in excellent yields in less time than the methods already reported.
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Format |
176656 bytes
application/pdf |
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Language |
en
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Subject |
Aldehydes
Phase transfer catalyst Dihydropyrimidinone |
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Title |
Tetrabutylammonium Hydrogensulphate Catalyzed Efficient Synthesis of Glycosyl(aryl) Dihydropyrimidinones
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Type |
Article
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