2,4,5-Trichlorophenyl-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)methylcarbamates: Synthesis, isolation, characterization and utility in the synthesis of dipeptidyl ureas
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Babu, Vommina V Suresh
Kantharaju |
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| Date |
2010-05-31T04:52:56Z
2010-05-31T04:52:56Z 2005-05 |
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/9090 |
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| Description |
1046-1053
An efficient synthesis of 2,4,5-trichlorophenyl-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)methylcarbamates employing isocyanates derived from several Fmoc-amino acids has been described. All the carbamates made have been obtained as crystalline solids and are fully characterized by IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR and mass spectrometry. They have been used as building blocks for the synthesis of several dipeptidyl urea esters. The coupling of carbamates with <i>N,O</i>-bis[trimethylsilyl]amino acids resulted in Fmoc-protected dipeptide urea acids in good yield as well as purity. All the dipeptidyl urea esters and acids made have been well characterized. |
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| Language |
en_US
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| Publisher |
CSIR
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| Relation |
<b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 K</b>
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| Source |
IJC-B Vol.44B(05) [May 2005]
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| Title |
2,4,5-Trichlorophenyl-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)methylcarbamates: Synthesis, isolation, characterization and utility in the synthesis of dipeptidyl ureas
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| Type |
Article
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