Non-invasive oral cancer detection from saliva using zinc oxide-reduced graphene oxide nanocomposite based bioelectrode
IR@NPL: CSIR-National Physical Laboratory, New Delhi
View Archive Info| Field | Value | |
| Title |
Non-invasive oral cancer detection from saliva using zinc oxide-reduced graphene oxide nanocomposite based bioelectrode
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| Creator |
Verma, Shilpi
Singh, Surinder P. |
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| Subject |
Materials Science
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| Description |
Multifunctional materials with excellent biocompatibility and electron-transport properties are critical for the pursuit of point-of-care biosensing devices. The authors report the synthesis of zinc oxide-reduced graphene oxide (ZnO-rGO) nanocomposite for the fabrication of an electrochemical immunosensing test-bed for noninvasive onsite detection of oral cancer biomarker (interleukin-8, IL8). The immunosensor showed successful detection of IL8 at low concentration ranges, i.e., 100 fg/mL-5 ng/mL with a sensitivity of 12.46 +/- 0.82 mu A mL/ng and a detection limit of 51.53 +/- 0.43 pg/mL. These results have been validated through in vitro investigations using real saliva samples spiked with IL8.
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| Publisher |
Materials Research Society
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| Date |
2019-12
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://npl.csircentral.net/4401/1/Non-invasive%20oral%20cancer%20detection%20from%20saliva%20using%20zinc%20oxide%E2%80%93reduced%20graphene%20oxide%20nanocomposite%20based%20bioelectrode.pdf
Verma, Shilpi and Singh, Surinder P. (2019) Non-invasive oral cancer detection from saliva using zinc oxide-reduced graphene oxide nanocomposite based bioelectrode. MRS Communications, 9 (4). pp. 1227-1234. ISSN 2159-6859 |
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| Relation |
http://npl.csircentral.net/4401/
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