Synthesis, characterization and antibacterial activity of benzimidazole derivatives carrying quinoline moiety
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Title |
Synthesis, characterization and antibacterial activity of benzimidazole derivatives carrying quinoline moiety
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| Creator |
Gowda, Janardhana
Khader, A M A Kalluraya, Balakrishna Hidayathulla, Syed |
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| Subject |
Benzimidazoles
Quinolines 2-(1H-benzimidazol-2-yl)thieno[2,3-]quinoline Antibacterial activity |
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| Description |
1491-1495
A new series 2-(1<i>H</i>-benzimidazol-2-yl)-6-substitutedthieno[2,3-<i>b</i>]quinolines <b style="">4</b> have been synthesized by a one-step process in which 2-(chloromethyl)-1<i>H</i>-benzimidazole <b style="">2</b>/2-(mercaptomethyl)-1<i>H-</i>benzimidazoles <b style="">6</b> undergo nucleophilic substitution and cyclisation with 2-mercaptoquinoline-3-carbaldehyde <b style="">1</b>/2-chloroquinoline-3-carbaldehyde <b style="">5</b>.<b style=""> </b>The compounds have been synthesized by two methods to select a method of higher yield. The newly synthesized compounds have been characterized by IR, CHNS analysis, LC-MS and <sup>1</sup>H NMR and also screened for antibacterial activity. |
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| Date |
2011-10-10T11:17:37Z
2011-10-10T11:17:37Z 2011-10 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/12852 |
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| Language |
en_US
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.50B(10) [October 2011]
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