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Synthesis and antimicrobial activity of linked heterocyclics containing pyrazole-pyrimidine rings

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Title Synthesis and antimicrobial activity of linked heterocyclics containing pyrazole-pyrimidine rings
 
Creator Reddy, Ch Sanjeeva
Devi, M Vani
Kumar, G Rajesh
Rao, L Sanjeeva
Nagaraj, A
 
Subject Pyrazole
Pyrimidine
Antibacterial activity
Antifungal activity
 
Description 1181-1186
New series of 4-(aryl/hetaryl)-6-(3,5-dimethyl-1-phenyl-1<i>H</i>-4-pyrazolyl)-2-pyrimidinamine <b>5a-j</b> has been prepared and confirmed by IR, NMR, MS and elemental analyses. All the synthesized compounds have been tested for their antimicrobial activity against bacteria and fungi. Among the synthesized compounds, the compounds containing 4-nitrophenyl <b style="">5c</b>,<b style=""> </b>2-furyl<b style=""> 5h</b> and 2-thiazolyl <b style="">5j </b>at 6-position of pyrimidine ring are highly active against all the organisms employed.
 
Date 2011-09-07T08:41:37Z
2011-09-07T08:41:37Z
2011-09
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/12668
 
Language en_US
 
Rights <img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.50B(09) [September 2011]