Design, facile synthesis and biological evaluation of quinazoline containing pyrazolothiazolyl, triazinone and their ethoxyphthalimide derivatives
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
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Title |
Design, facile synthesis and biological evaluation of quinazoline containing pyrazolothiazolyl, triazinone and their ethoxyphthalimide derivatives
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Creator |
Dangi, Raja Ram
Hussain, Nasir Joshi, Ajit Pemawat, Gangotri Talesara, Ganpat Lal |
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Subject |
Benzoxazine
Quinazoline Pyrazole Schiff base Bromoethoxyphthalimide |
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Description |
1165-1172
A series of 3-(4-substituted benzylidene)-4-N-ethoxyphthalimido-6-phenyl-3,4-dihydro-2<i>H</i>-[1,2,4]triazino[2,3-<i>c</i>]quinazolin-2-one <b style="">6a-d</b> and 3-[3-(4-substituted benzylidene-5-phenyl- 2-N-ethoxyphthalimido-3,3<i style="">a</i>-dihydro-2<i>H</i>-pyrazolo[3,4-<i>d</i>][1,3]thiazol-6(5<i>H</i>)-yl)]-2-phenylquinazolin-4(3<i>H</i>)-one <b style="">11a-d</b> have been designed and synthesized starting from benzoxazine <b style="">1</b>. The structure of all synthesized compounds has been established by IR, <sup>1</sup>H and <sup>13</sup>C NMR and mass spectral studies. These compounds have been screened for antimicrobial activities in order to evaluate the possibility of the derivatives to be used as potential chemotherapeutic agents. |
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Date |
2011-09-07T08:40:52Z
2011-09-07T08:40:52Z 2011-09 |
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Type |
Article
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Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/12666 |
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Language |
en_US
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Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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Publisher |
NISCAIR-CSIR, India
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Source |
IJC-B Vol.50B(09) [September 2011]
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