Zephgrabetaine: A New Betaine-type Amaryllidaceae Alkaloid from Zephyranthes grandiflora
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Zephgrabetaine: A New Betaine-type Amaryllidaceae Alkaloid from
Zephyranthes grandiflora
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| Creator |
Katocha, Deepali
Kumarb, Dharmesh Sharma, Upendra Kumar, Neeraj Padwad, Yogendra S. Lal, Brij Singh , Bikram |
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| Subject |
Natural Product Chemistry
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| Description |
Zephgrabetaine (1), a new betaine type Amaryllidaceae alkaloid, along with seven known alkaloids, lycorine, galanthine, lycoramine, hamayne,
haemanthamine, tortuosine, and ungeremine were isolated from the bulbs of Zephyranthes grandiflora and their structures elucidated by spectroscopic data
analysis. The isolated alkaloids were tested for in vitro cytotoxic activities against two cell lines, C-6 (rat glioma cells) and CHO-K1 (Chinese hamster ovary
cells). A dose dependent cytotoxic effect was exhibited by all the alkaloids on these two cancer cell lines with prominent activity of lycorine and
haemanthamine.
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| Date |
2013
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/1337/1/105_Zephgrabetaine_A_new.pdf
Katocha, Deepali and Kumarb, Dharmesh and Sharma, Upendra and Kumar, Neeraj and Padwad, Yogendra S. and Lal, Brij and Singh , Bikram (2013) Zephgrabetaine: A New Betaine-type Amaryllidaceae Alkaloid from Zephyranthes grandiflora. Journal of Natural Product Communications, 8 (2). pp. 161-164. |
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| Relation |
http://ihbt.csircentral.net/1337/
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