Biocatalysts for multicomponent Biginelli reaction: bovine serum albumin triggered waste-free synthesis of 3,4-dihydropyrimidin-2-(1H)-ones
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Biocatalysts for multicomponent Biginelli reaction:
bovine serum albumin triggered waste-free synthesis
of 3,4-dihydropyrimidin-2-(1H)-ones
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| Creator |
Sharma , U K
Sharma, Nandini Kumar, Rajesh Sinha, Arun K |
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| Subject |
Natural Product Chemistry
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| Description |
Bovine serum albumin (BSA) promoted simple
and efficient one-pot procedure was developed for the
direct synthesis of 3,4-dihydropyrimidin-2(1H)-ones
including potent mitotic kinesin Eg5 inhibitor monastrol
under mild reaction conditions. The catalyst recyclability
and gram scale synthesis have also been demonstrated to
enhance the practical utility of process.
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| Date |
2013
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/1332/1/107_Biocatalysts.pdf
Sharma , U K and Sharma, Nandini and Kumar, Rajesh and Sinha, Arun K (2013) Biocatalysts for multicomponent Biginelli reaction: bovine serum albumin triggered waste-free synthesis of 3,4-dihydropyrimidin-2-(1H)-ones. Journal of Amino Acids, 44. pp. 1031-1037. |
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| Relation |
http://ihbt.csircentral.net/1332/
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