Systematic transcriptome wide analysis of lncRNA- miRNA interactions.
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
View Archive Info| Field | Value | |
| Title |
Systematic transcriptome wide analysis of lncRNA-
miRNA interactions.
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| Creator |
Jalali, Saakshi
Bhartiya, Deeksha Scaria, Vinod |
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| Subject |
G1 Genome informatics (General)
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| Description |
Background
Long noncoding RNAs (lncRNAs) are a recently discovered class of non-protein coding RNAs
which have now increasingly been shown to be involved in a wide variety of biological
processes as regulatory molecules. The functional role of many of the members of this class has
been an enigma, except a few of them like Malat and HOTAIR. Little is known regarding the
regulatory interactions between noncoding RNA classes. Recent reports have suggested that
lncRNAs could potentially interact with other noncoding RNAs including miroRNAs
(miRNAs) and modulate their regulatory role through interactions. We hypothesized that long
noncoding RNAs could participate as a layer of regulatory interactions with miRNAs. The
availability of genome-scale datasets for argonaute targets across human transcriptome has
prompted us to reconstruct a genome-scale network of interactions between miRNAs and
lncRNAs.
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://openaccess.igib.res.in/145/1/arxiv_01082012.pdf
Jalali, Saakshi and Bhartiya, Deeksha and Scaria, Vinod Systematic transcriptome wide analysis of lncRNA- miRNA interactions. Systematic transcriptome wide analysis of lncRNA- miRNA interactions.. |
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| Relation |
http://openaccess.igib.res.in/145/
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