BioSuite: A comprehensive bioinformatics software package (A unique industry–academia collaboration)
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
View Archive Info| Field | Value | |
| Title |
BioSuite: A comprehensive bioinformatics
software package (A unique industry–academia
collaboration)
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| Creator |
BioSuite Team, The Nmitli
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| Subject |
BI1 Bioinformatics (General)
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| Description |
T HE l ast decade has witnessed an exponential growth of
information in the field of biological macromolecules
such as proteins and nucleic acids and their interactions
with other molecules. Computational analysis and predictions
based on such information are increasingly becoming an
essential and integral part of modern biology. With rapid
advances in the area, there is a growing need to develop
versatile bioinformatics software packages, which are effi-
cient and incorporate the latest developments in this field.
In view of this, the Council of Scientific and Industrial
Research, India, undertook an initiative to promote a unique
industry–academia collaboration, to develop a compre-hensive bioinformatics software package, under its New
Millennium Initiative for Technology Leadership in India
programme. BioSuite, a product of that effort, has been
developed by Tata Consultancy Services who took the
primary coding responsibility with significant backing
from a large academic community who participated on
advisory roles through the project period.
BioSuite integrates the functions of macromolecular
sequence and structural analysis, chemoinformatics and
algorithms for aiding drug discovery. The suite organized
into four major modules, contains 79 different programs,
making it one of the few comprehensive suites that caters
to a major part of the spectrum of bioinformatics applica-
tions. The four major modules, (a) Genome and proteome
sequence analysis, (b) 3D modelling and structural analysis,
(c) Molecular dynamics simulations and (d) Drug design,
are made available through a convenient graphics-user in-
terface along with adequate documentation and tutorials.
The unique partnership with academia has also ensured
that the best available methodology has been adopted for each
of the 79 programs, which has been thoroughly evaluated
in several stages, leading to high scientific value of the
suite. The software, apart from having the advantage of
running on a Linux platform on a personal computer, is
also flexible, modular, and allows for newer algorithms to
be plugged into the overall framework. The package will
be valuable for high quality academic research, industrial
research and development and for teaching purposes, both
locally within the country as well as in the international
arena. A full list of the programs as well as their example
usage can be found at http://www.atc.tcs.co.in/bioinfo/
publications/biosuite_paper.pdf.
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| Date |
2007-01-10
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://openaccess.igib.res.in/109/1/biosuite_currentscience.pdf
BioSuite Team, The Nmitli (2007) BioSuite: A comprehensive bioinformatics software package (A unique industry–academia collaboration). BioSuite, 92 (1). pp. 29-38. |
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| Relation |
http://openaccess.igib.res.in/109/
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